HCA 699 What is the difference between statistically significant evidence and clinically significant evidence?

Grand Canyon University HCA 699 What is the difference between statistically significant evidence and clinically significant evidence?-Step-By-Step Guide

This guide will demonstrate how to complete the Grand Canyon University HCA 699 What is the difference between statistically significant evidence and clinically significant evidence? assignment based on general principles of academic writing. Here, we will show you the A, B, Cs of completing an academic paper, irrespective of the instructions. After guiding you through what to do, the guide will leave one or two sample essays at the end to highlight the various sections discussed below.

How to Research and Prepare for HCA 699 What is the difference between statistically significant evidence and clinically significant evidence?                            

Whether one passes or fails an academic assignment such as the Grand Canyon University HCA 699 What is the difference between statistically significant evidence and clinically significant evidence?  depends on the preparation done beforehand. The first thing to do once you receive an assignment is to quickly skim through the requirements. Once that is done, start going through the instructions one by one to clearly understand what the instructor wants. The most important thing here is to understand the required format—whether it is APA, MLA, Chicago, etc.

After understanding the requirements of the paper, the next phase is to gather relevant materials. The first place to start the research process is the weekly resources. Go through the resources provided in the instructions to determine which ones fit the assignment. After reviewing the provided resources, use the university library to search for additional resources. After gathering sufficient and necessary resources, you are now ready to start drafting your paper.

How to Write the Introduction for HCA 699 What is the difference between statistically significant evidence and clinically significant evidence?                          

The introduction for the Grand Canyon University HCA 699 What is the difference between statistically significant evidence and clinically significant evidence?  is where you tell the instructor what your paper will encompass. In three to four statements, highlight the important points that will form the basis of your paper. Here, you can include statistics to show the importance of the topic you will be discussing. At the end of the introduction, write a clear purpose statement outlining what exactly will be contained in the paper. This statement will start with “The purpose of this paper…” and then proceed to outline the various sections of the instructions.

How to Write the Body for HCA 699 What is the difference between statistically significant evidence and clinically significant evidence?                          

After the introduction, move into the main part of the HCA 699 What is the difference between statistically significant evidence and clinically significant evidence?  assignment, which is the body. Given that the paper you will be writing is not experimental, the way you organize the headings and subheadings of your paper is critically important. In some cases, you might have to use more subheadings to properly organize the assignment. The organization will depend on the rubric provided. Carefully examine the rubric, as it will contain all the detailed requirements of the assignment. Sometimes, the rubric will have information that the normal instructions lack.

Another important factor to consider at this point is how to do citations. In-text citations are fundamental as they support the arguments and points you make in the paper. At this point, the resources gathered at the beginning will come in handy. Integrating the ideas of the authors with your own will ensure that you produce a comprehensive paper. Also, follow the given citation format. In most cases, APA 7 is the preferred format for nursing assignments.

How to Write the Conclusion for HCA 699 What is the difference between statistically significant evidence and clinically significant evidence?                          

After completing the main sections, write the conclusion of your paper. The conclusion is a summary of the main points you made in your paper. However, you need to rewrite the points and not simply copy and paste them. By restating the points from each subheading, you will provide a nuanced overview of the assignment to the reader.

How to Format the References List for HCA 699 What is the difference between statistically significant evidence and clinically significant evidence?                            

The very last part of your paper involves listing the sources used in your paper. These sources should be listed in alphabetical order and double-spaced. Additionally, use a hanging indent for each source that appears in this list. Lastly, only the sources cited within the body of the paper should appear here.

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Sample Answer for HCA 699 What is the difference between statistically significant evidence and clinically significant evidence? 

Re: Topic 6 DQ 2

“Clinical significance of a result is dependent on its implications on existing practice-treatment effect size being one of the most important factors that drives treatment decisions. LeFort suggests that the clinical significance should reflect “the extent of change, whether the change makes a real difference to subject lives, how long the effects last, consumer acceptability, cost-effectiveness, and ease of implementation”. Statistical significance is heavily dependent on the study’s sample size; with large sample sizes, even small treatment effects (which are clinically inconsequential) can appear statistically significant; therefore, the reader has to interpret carefully whether this “significance” is clinically meaningful” (Ranganathan, Pramesh, & Buyse, 2015, para. 2).

The difference between statistically significant evidence and clinically significant evidence is most clinical research that are statistically significant are often interpreted as being clinically important. On the other hand, statistical significance indicates the reliability of the study results typically reflects an impact as clinical practice. Statistically significant evidence is often times referred to as an absolute value of S is greater than the critical value this would ultimately give you the formula of the to the answer of the equation. Clinically significant evidence is more related to the abstract not so much based on the trend that usually most evidence would come from. The way each of these findings would be used to advance an evidenced based project would be very interesting. I think the more concrete method to use would be statistically significant evidence because it tends to lead more to the certain and concrete evidence more than a guess or some one’s opinion. When using clinically significant evidence it is more based on some one’s own research and the determination or conclusion they were able to come to using the formula or information they had at the time. These two different types of methods can be confusing at times because the user may not know what avenue to take but depending on the evidence you are currently looking for that will kind of steer you in the direction. Listening to what you are looking for is extremely important because picking the wrong evidence will have the information you receive be very incorrect.

References

Ranganathan, P., Pramesh, C. D., & Buyse, M. (2015). Common pitfalls in statistical analysis: Clinical versus statistical significance. Perspectives in Clinical Research, 6(3), 169-170. doi: https://doi-org.lopes.idm.oclc.org/10.4103/2229-3485.159943

Sample Answer 2 for HCA 699 What is the difference between statistically significant evidence and clinically significant evidence? 

It appears that people often misinterpret these two types of evidence as being one and the same. Mainly because there is a confusion that stems from the word significant as meaning it is literally important (Ranganathan, Pramesh, Buyse, 2015). For statistics specifically, it has a completely different implication than with clinically applicable findings (Ranganathan et al., 2015). So statistically significant is about “quantifying the probability of a study’s results being due to chance. Clinical significance, on the other hand, refers to the magnitude of the actual treatment effect” (Ranganathan et al., 2015, p.169).

When it comes to advancing an evidenced-based project it appears that clinical significance is more of what is being sought. Because it is about the findings that are related to the control groups and receiving the intervention being researched (Ranganathan et al., 2015). If the results are strong enough within their trial than it can greatly impact best practice (Ranganathan et al., 2015). If an intervention produces the results in favor of the hypothesis then it can be applied to real-life medical care. This strongly helps advance any evidenced-based project because of its established applications to care.

Now statistical significance is still important however it is far more dependent on several variables one of which is the sample size of the study (Ranganathan et al., 2015). The larger the sample size the more the findings can appear to be statistically significant even if the treatment effects are inconsequential (Ranganathan et al., 2015). There is more responsibility put on the readers evaluating the study to determine if the statistically significant findings are clinically applicable (Ranganathan et al., 2015). One such example of this was a study done on patients with advanced pancreatic cancer who received treatment with erlotinib plus gemcitabine versus a group who only received gemcitabine alone in their treatment (Ranganathan et al., 2015). The survival rates were found to be prolonged in the groups that received both treatments with a p-value being about 0.038 (Ranganathan et al., 2015). This translates to there being “only a 3.8% chance that this observed difference between the groups occurred by chance…and therefore, [is] statistically significant” (Ranganathan et al., 2015, p.170). Despite being statistically significant it shows the treatment effect did not produce enough of the median survival rate and is therefore clinically irrelevant when it comes to measuring the outcomes of this suggested combination (Ranganathan et al., 2015).

Overall for statistical significance, context is everything and is not as easily applied for EBP as the findings that are considered clinically significant. The best way to differentiate between the two is through the way that Melnyk & Fineout-Overholt explain it which is that clinical significance is how the impact the findings will have on clinical practice, and statistical significance is that the results did not occur by happenstance (2019). Thus, as a reader of these studies, it is important to be cognizant of these two types of findings and be able to infer them correctly when considering an application to practice. Each does offer something to advance an EBP but may not be applicable in every situation. This has to be decided once the variables are considered and ruled out.

Ranganathan, P., Pramesh, C., & Buyse, M. (2015). Common pitfalls in statistical analysis: Clinical versus statistical significance. Perspectives in Clinical Research, 6(3), 169-170. Retrieved from http://www.picronline.org/article.asp?issn=2229-3485;year=2015;volume=6;issue=3;spage=169;epage=170;aulast=Ranganathan

Melnyk, B., & Fineout-Overholt, E. (2019). Evidence-based practice in nursing & healthcare a guide to best practice 4th edition [Ebook Version]. Retrieved from https://www.gcumedia.com/digital-resources/wolters-kluwer/2018/evidence-based-practice-in-nursing-and-healthcare_a-guide-to-best-practice_4e.php

HCA 699 Week 7 DQ 1 Sample Answer

According to Arkansas State University (2018), “One of the key principles in medicine today is evidence-based practice in nursing (EBP). This is the practice of medicine based on solid research, and it adheres to standards for high quality and safety, all while focusing on patients’ needs.” EBP Projects would be the most effective the reason why I say this is EBP Projects are more preventative than it is trying to predict the future. EBP Projects take into consideration the fact that patients are better off using evidence-based research to help the patients understand and recover. EBP takes into consideration infection control because the last thing a patient wants to do is come into a hospital and get an infection because of something the hospital failed to do. These things help get nurses to the next level by preparing them to be able to do the proper research and becoming better problem solvers versus being reactive they become more proactive(Arkansas State University, 2018). The best way to make that all appropriate audiences receive the correct information is by making it available to everyone who needs it. This information can be available via the web and also in the office by brochures. Most patients have access to a variety of electronic manuals and ways to view the information now because almost everyone owns either a cell phone or a computer now. With the access to Google most patients have access to more information now than they have ever had. This is important because information is the key and information is can help keep patients updated on new information that otherwise they may not have had accessed to. This is a process that will continue to improve over the years as healthcare continues to improve and technology continues to improve. Melnyk & Fineout-Overholt (2019) states “If an individual with in-depth knowledge of EBP and research is not available within the organization, establishing a partnership with an academic institution can help to facilitate the development of a program. 

Arkansas State University. (2018). 4 Examples of Evidence-Based Practice in Nursing. Retrieved from https://degree.astate.edu/articles/nursing/examples-of-evidence-based-practice-in-nursing.aspx 

Melnyk, B. M., & Fineout-Overholt, E. (Eds.). (2019). Evidence-based practice in nursing and healthcare: A guide to best practice (4th ed.). Philadelphia, PA: Wolters Kluwer. ISBN-13: 9781496384539